Advances and Outlooks in Cetacean Gastrointestinal Microbiome Research
The microbiome residing in the gastrointestinal tract,serving as the host's second genome,is closely linked to the intake of nutrient and the immune system's de-fense mechanism of hosts.Compared to terrestrial mammals,the gastrointestinal microbi-ome of marine mammal cetacean has received less attention.Several studies have dem-onstrated that the cetacean gastrointestinal microbiome is highly affected by factors such as diet and habitat environment.Currently,the primary approaches for these studies are high-throughput sequencing based on fecal samples.This review paper summarized and analyzed the research methodologies,community structure,functional characteristics,and regula-tory strategies of the cetacean gastrointestinal microbiome,and several potential avenues for future development were also proposed.