Effect of High Concentration of Melatonin on FGF20 Gene Expression in Muskrat Scent Glands
Muskrat(Ondatra zibethicus)is a spice and fur animal with high economic value.Melatonin(MT)is commonly used in the production of some fur-bearing animals for higher benefits,but the role of MT on the development of muskrat scent glands is un-clear.In order to explore the effect of high concentration MT on the expression of fibroblast growth factor 20(FGF20)gene in muskrat's gland,RT-qPCR technique was used to detect the transcription level of FGF20 gene in muskrat gland of high concentration MT treatment group and control group.The results showed that the ex-pression level of FGF20 gene in the control group was 33.95 times higher than that in the high concentration MT treatment group(each muskrat was implanted with one capsule containing 20 mg MT),and the difference was extremely significant(p<0.01).It is speculated that FGF20 gene is involved in the regulation of the development of scent gland,and a high con-centration of MT inhibits the expression of FGF20 gene.The results of this study provide a basis for exploring the improve-ment of fertility and fragrance production of muskrats with appropriate use of MT.
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