Graphene oxide coating was prepared on the surface of pure titanium via using 3-aminopropyltriethoxysilane.Scanning electron microscopy,raman spectroscopy,X-ray energy spectrometer and X-ray photoelectron spectroscopy were adopted to characterize the morphology,structure and composition of the coating.The biological activity of titanium sheets in different treatment groups was evaluated via in vitro cytotoxicity test,acute hemolysis test and SBF simulated body fluid immersion test.The results showed that the graphene oxide coating was prepared on the surface of pure titanium by silane coupling agent.The in vitro cytotoxicity test and acute hemolysis test preliminarily confirmed that the composite coating had good biocompatibility.The SBF simulated body fluid immersion experiment showed that the graphene oxide coating could improve the ability of hydroxyapatite deposition on the surface of pure titanium.
关键词
纯钛/硅烷偶联剂/氧化石墨烯/生物相容性/细胞培养
Key words
pure titanium/silane coupling agent/graphene oxide/biocompatibility/cell culture
维普
万方数据