摘要
目的 观察正常人手握拳反应的脑功能磁共振成像特点,为脑血管意外致运动功能障碍患者脑功能磁共振成像研究提供理论依据.方法 选择12例健康志愿者,行实时动态脑功能磁共振成像.每例分别接受以下3个任务:(1)左手握拳.(2)右手握拳.(3)左右手同时握拳.脑功能图像资料采用脑功能成像AFNI分析软件进行数据分析.结果 在F值(6,1121),P=0.005条件下,左手握拳激活的脑功能区有右中央前回、左顶叶、右颞上回、右顶叶、右海马回、右额上回、右额内侧回、左楔前叶、右顶上小叶、右额中回、左额上回;右手握拳激活的脑功能区有左中央前回、左中央后回、右顶叶、右额内侧回;双手同时握拳激活的脑功能区有左中央前回、左中央后回、右中央前回、右中央后回.结论 手运动(握拳)在脑内有特定的功能区激活;双手同时握拳激活的脑功能区集中于双侧运动区;单手握拳激活的脑功能区除运动区外,还有辅助运动区参与;与右利手相比,左手运动激活的脑功能区范围更广泛.
Abstract
Objective To observe the characteristic of the functional magnetic resonance imaging (fMRI) brain map in health adult undergoing clenching and relaxing the fist, for exploring the essence of the fMRI brain map in patients suffering from motor dysfunction by cerebrovascular accidents. Methods Twelve healthy volunteers had been chosen to partake the experience. Everyone had accomplished the following three actions separately: (1) Only clenching and relaxing the fist of left hand. (2) Only clenching and relaxing the fist of right hand. (3) Clenching and relaxing the fist of both hands at one time. The data had been analyzed statistically using analysis of functional neuroimages (AFNI) software. Results Under condition of F (6,1121), P = 0.005. Only clenching and relaxing the fist of left hand had gained the following brain functional area: right precentral gyms, left parietal,right superior temporal gyrus,right parietal, right parahippocampal gyrus, right superior frontal gyrus, right medial frontal gyrus, left precuneus, right superior parietal lobule, right middle frontal gyrus, left superior frontal gyrus. Only clenching and relaxing the fist of right hand had gained the following brain functional area: left precentral gyms, left postcentral gyrus right parietal, right medial frontal gyrus. Clenching and relaxing the fist of beth hands simultaneously had gained the following brain functional area: left precentral gyms,left postcentral gyrus, right precentral gyrus, right postcentral gyrus. Conclusions Hand movement (clenching and relaxing the fist) has its own specific brain activated areas. The brain areas activated by clenching and relaxing the fist of both hands simultaneously concentrate in the motor area of both cerebral hemisphere. The brain areas activated by clenching and relaxing the fist of single hand contain not only the motor area, but also the supplementary motor area. As compared with the right handedness, the brain areas activated by clenching and relaxing the fist of left hand is more widespread.
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