A case-control study on the incidence factors of esophageal cancer
卞荣荣 1吕春晖 1杭兆康 1刘飞 1贾安
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作者信息
1. 南京市六合区人民医院肿瘤内科，南京 211500
折叠
摘要
目的 探讨食管癌发病的危险因素与保护因素，为预防、治疗及后期干预提供策略。 方法 采用回顾性研究的方法，选择2020年7月至2023年2月南京市六合区人民医院收治的经病理确诊的食管癌患者150例（观察组）和同期骨科非肿瘤患者150例（对照组）为研究对象，进行问卷调查，分析食管癌发病的独立危险因素和保护因素。 结果 单因素Logistic回归分析结果表明，吸烟、饮酒、饮烫茶（热饮>65 ℃）、食用生硬食物、食用腌制食品频率、食用水果频率、食用蔬菜频率、发脾气次数、经济收入、食用面包次数是影响食管癌发病的因素（P<0.05）。多因素Logistic回归分析结果表明，吸烟、食用水果≤3次/周、以前饮酒但是现在不饮酒、不吃生硬食物是影响食管癌发病的因素（P<0.05）。 结论 吸烟和食用水果≤3次/周是食管癌发病的独立危险因素，以前饮酒但是现在不饮酒和不吃生硬食物是食管癌发病的独立保护因素。 Objective To explore the risk factors and protective factors for esophageal cancer, and provide strategies for prevention, clinical treatment and later-stage intervention. Methods A total of 150 patients with pathologically confirmed esophageal cancer admitted to Nanjing Liuhe District People′s Hospital from July 2020 to February 2023 were selected as the observation group, and 150 non-tumor patients hospitalized in the department of orthopedics during the same period were selected as the control group. A questionnaire survey was conducted to analyze the independent risk factors and independent protective factors for esophageal cancer. Results Univariate Logistic regression analysis showed that smoking, alcohol consumption, drinking hot tea (hot drinking >65 ℃), eating hard food, frequency of consuming pickled food, frequency of consuming fruits, frequency of consuming vegetables, frequency of getting angry, economic income and frequency of consuming bread were factors affecting the incidence of esophageal cancer ( P<0.05). Multivariate Logistic regression analysis showed that smoking, consuming fruits ≤3 times per week, previously drinking alcohol but currently not drinking, and not eating hard food were factors affecting the incidence of esophageal cancer (P<0.05). Conclusions Smoking and consuming fruits ≤3 times per week are independent risk factors for esophageal cancer, while previously drinking alcohol but currently not drinking and not eating hard food are independent protective factors for esophageal cancer.
Abstract
Objective To explore the risk factors and protective factors for esophageal cancer, and provide strategies for prevention, clinical treatment and later-stage intervention. Methods A total of 150 patients with pathologically confirmed esophageal cancer admitted to Nanjing Liuhe District People′s Hospital from July 2020 to February 2023 were selected as the observation group, and 150 non-tumor patients hospitalized in the department of orthopedics during the same period were selected as the control group. A questionnaire survey was conducted to analyze the independent risk factors and independent protective factors for esophageal cancer. Results Univariate Logistic regression analysis showed that smoking, alcohol consumption, drinking hot tea (hot drinking >65 ℃), eating hard food, frequency of consuming pickled food, frequency of consuming fruits, frequency of consuming vegetables, frequency of getting angry, economic income and frequency of consuming bread were factors affecting the incidence of esophageal cancer ( P<0.05). Multivariate Logistic regression analysis showed that smoking, consuming fruits ≤3 times per week, previously drinking alcohol but currently not drinking, and not eating hard food were factors affecting the incidence of esophageal cancer (P<0.05). Conclusions Smoking and consuming fruits ≤3 times per week are independent risk factors for esophageal cancer, while previously drinking alcohol but currently not drinking and not eating hard food are independent protective factors for esophageal cancer.
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