医师在线2024,Vol.14Issue(5) :17-20.

泸县体检中心机会性结肠镜筛查结直肠癌结果及结直肠癌危险因素分析

Opportunistic colonoscopy screening results for colonrectal cancer in Luxian physical examination center and analysis of risk factors for colonrectal cancer

康明祥 赵俊佳 宋莉 张旅君 季国辉
医师在线2024,Vol.14Issue(5) :17-20.

泸县体检中心机会性结肠镜筛查结直肠癌结果及结直肠癌危险因素分析

Opportunistic colonoscopy screening results for colonrectal cancer in Luxian physical examination center and analysis of risk factors for colonrectal cancer

康明祥 1赵俊佳 1宋莉 1张旅君 1季国辉1
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作者信息

  • 1. 泸县人民医院消化内科,四川泸州 646100
  • 折叠

摘要

目的 分析体检人群机会性结肠镜筛查结直肠癌(CRC)结果及CRC发病的危险因素.方法 采用问卷调查方式,对2021年7月~2022年12月在泸县医院体检中心接受机会性结肠镜筛查的359例体检者进行调查,收集筛查结果、年龄和性别等一般特征、饮酒和吸烟等生活方式、腹痛和大便性状改变等症状,以及既往病史和肿瘤家族史等信息,进行单因素分析,运用多因素Logistic回归分析CRC发病的危险因素,采用受试者工作特征曲线(ROC)确定危险因素的临界值.结果 359例机会性结肠镜筛查共发现结直肠腺瘤87例(24.2%),非结直肠腺瘤272例(75.8%).单因素分析显示,两组的性别、年龄和体重指数(BMI)有统计学差异(P<0.05).多因素Logistic回归分析表明,年龄是结直肠腺瘤发病的危险因素(P<0.05).ROC确定年龄临界值是45岁(灵敏度71.3%,特异度41.5%).结论 结直肠腺瘤缺乏特异性临床表现,但在机会性结肠镜筛查中有较高的结直肠腺瘤检出率.年龄是结直肠腺瘤发病的主要危险因素,因此尤其要关注45岁以上成年人的CRC筛查.

Abstract

Objective To analyze the results of opportunistic colonoscopy screening for colonrectal cancer(CRC)in physical examination population and the risk factors of CRC.Methods A questionnaire survey was conducted to investigate 359 cases of physical examinees who underwent opportunistic colonoscopy screening in the physical examination center of Luxian Hospital from July 2021 to December 2022.The results of colonoscopy,general characteristics including age and gender,lifestyle factors including drinking and smoking,symptoms including abdominal pain and changes in stool traits,as well as information including past medical history and family history of tumors were collected for single factor analysis.Multivariate Logistic regression analysis was used to find out the risk factors of CRC,and the receiver operating characteristic curve(ROC)was used to determine the critical value for the identified risk factors.Results A total of 87 cases(24.2%)of colorectal adenoma and 272 cases(75.8%)of non-colorectal adenoma were found in 359 cases of colonoscopic opportunistic screening.Single factor analysis showed that there were statistically significant differences in gender,age,and body mass index(BMI)between the two groups(P<0.05).Multivariate Logistic regression analysis showed that age was a risk factor for colorectal adenoma(P<0.05).The ROC determined that the age threshold was 45 years old(sensitivity 71.3%,specificity 41.5%).Conclusion Colorectal adenomas lack specific clinical manifestations,but there is a higher incidence of adenoma detection in opportunistic colonoscopy screening.Age is the main risk factor for colorectal adenoma.Special attention should be paid to CRC screening in adults over 45 years old.

关键词

结直肠癌/机会性筛查/结肠镜

Key words

Colorectal cancer/Opportunistic screening/Colonoscopy

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基金项目

四川省医学会消化内镜专委会(捷祥)专项科研课题(2021XHNJ38)

出版年

2024
医师在线

医师在线

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