Objective To observe the association between serum amyloid A(SAA),serum high-sensitive C-reactive protein(hs-CRP)and the characteristics of coronary atherosclerotic plaque.Methods A total of 123 patients with coronory heart disease who had undergone coronary angiography(CAG)and intravascular ultrasound(IVUS)from April 2021 to May 2022 were selected.According to the clinical symptoms,electrocardiogram and CAG results,the patients were divided into stable angina pectoris(SAP)group(78 cases)and acute coronary syndromes(ACS)group(45 cases).The general clinical data,related serum indicators,SAA and hs-CRP levels were compared between the two groups.According to the characteristics of coronary atherosclerotic plaques obtained by IVUS,the patients were divided into fibrous plaques group(46 cases),lipid plaques group(24 cases),mixed plaques group(22 cases),and calcified plaques group(31 cases).The correlation between the characteristics of cornonary atherosclerotic plaque and serum indexes was compared.Results Serum SAA and hs-CRP levels in the ACS group were significantly higher than those in the SAP group(P<0.05);Serum SAA and hs-CRP levels in lipid plaques group were higher than those in other plaque groups(P<0.05).Conclusion The serum levels of SAA and hs-CRP are significantly higher than those in the SAP group,and they are more likely to form unstable plaques,which can assist IVUS to evaluate plaque vulnerability.
维普
万方数据