慢加急性肝衰竭的预后研究进展
Research progress in the prognosis of acute-on-chronic liver failure
刘文丽 1甘建和1
作者信息
- 1. 苏州大学附属第一医院,江苏苏州 215000
- 折叠
摘要
慢加急性肝衰竭(Acute-on-chronic liver failure,ACLF)是一种在慢性肝病基础上短时间内进展为多器官功能衰竭的临床综合征,与炎症反应、细菌感染、免疫缺陷和肠道生态异常等有关,其特征是病情严重、进展迅速、治疗反应差、预后不良.本文归纳了相关的预后评估体系,主要包括预后评分系统、血清学指标及其他一些复合指标,旨在早期及时评估ACLF患者的预后,从而合理配置医疗资源,延长患者的生存期.
Abstract
Acute-on-chronic liver failure(ACLF)is a clinical syndrome that rapidly progresses to multiple organ failure on the basis of chronic liver disease.It is related to inflammatory reactions,bacterial infections,immune deficiencies and intestinal ecological abnormalities.It is characterized by severe condiction,rapid progression,poor treatment response and poor prognosis.This article summarizes the relevant prognostic evaluation systems,mainly including prognostic scoring systems,serological indicators and other composite indicators.It refers to timely evaluation of the prognosis of ACLF patients in the early stage,in order to allocate medical resources reasonably and extend the patient's survival period.
关键词
慢加急性肝衰竭/预后/评分系统Key words
Acute-on-chronic liver failure/Prognosis/Scoring systems引用本文复制引用
基金项目
"十三五"国家科技重大专项项目(2017ZX10203201002-002)
出版年
2024
NETL
NSTL
万方数据