医师在线2024，Vol.14Issue(12) ：40-42.

脑苷肌肽联合七叶皂苷钠辅助治疗急性脑出血患者的效果观察

Effect observation of cerebroside carnosine combined with sodium aescinate in adjuvant treatment of patients with acute cerebral hemorrhage

赵甦
医师在线2024，Vol.14Issue(12) ：40-42.
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脑苷肌肽联合七叶皂苷钠辅助治疗急性脑出血患者的效果观察

Effect observation of cerebroside carnosine combined with sodium aescinate in adjuvant treatment of patients with acute cerebral hemorrhage

赵甦1
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作者信息

  • 1. 武进中医医院神经外科,江苏常州 213161
  • 折叠

摘要

目的 探究脑苷肌肽联合七叶皂苷钠辅助治疗急性脑出血患者的效果.方法 选取2021年7月～2023年7月在我院治疗的80例急性脑出血患者,随机分为两组,各40例.对照组采用常规治疗,包括止血、脱水、抗感染、控制血压和血糖及抗血小板聚集等对症支持治疗,观察组在对照组基础上加用脑苷肌肽联合七叶皂苷钠辅助治疗.比较两组患者的神经功能、日常生活能力、脑血肿量和脑水肿量、实验室指标及不良反应等,并评估两组患者的临床疗效.结果 治疗后,观察组的美国国立卫生研究院卒中量表(NIHSS)、改良Rankin量表(mRS)评分均低于对照组,Barthel指数(BI)评分高于对照组(P＜0.05);治疗后,观察组的脑血肿量和脑水肿量均低于对照组(P＜0.05);治疗后,观察组白细胞介素(IL)-6(IL-6)、IL-10等实验室指标和总有效率均优于对照组(P＜0.05);观察组的不良反应总发生率低于对照组(P＜0.05).结论 急性脑出血患者采用脑苷肌肽联合七叶皂苷钠辅助治疗的效果较佳,可有效促进患者神经功能恢复,减轻脑水肿程度,进而提高患者的日常生活能力.

Abstract

Objective To explore the effect of cerebroside carnosine combined with sodium aescinate in the adjuvant treatment of patients with acute cerebral hemorrhage.Methods A total of 80 patients with acute cerebral hemorrhage treated in our hospital from July 2021 to July 2023 were selected and randomly divided into two groups,with 40 cases in each group.The control group was treated with routine treatment,including hemostasis,dehydration,anti-infection,control of blood pressure and blood glucose,anti-platelet aggregation and other symptomatic and supportive treatment.The observation group was treated with cerebroside carnosine combined with sodium aescinate on the basis of the control group.The neurological function,daily living ability,cerebral hematoma volume,cerebral edema volume,laboratory indexes and adverse reactions were compared between the two groups,and the clinical efficacy of the two groups was evaluated.Results After treatment,the scores of National Institutes of Health Stroke Scale(NIHSS)and modified Rankin Scale(mRS)scores in the observation group were lower than those in the control group,and the Barthel index(BI)scores was higher than that in the control group(P<0.05).After treatment,the amount of cerebral hematoma and cerebral edema in the observation group were lower than those in the control group(P<0.05).After treatment,the laboratory indexes such as interleukin(IL)-6(IL-6)and IL-10 and the total effective rate in the observation group were better than those in the control group(P<0.05).The overall incidence of adverse reactions in the observation group was lower than that in the control group(P<0.05).Conclusion The effect of cerebroside carnosine combined with sodium aescinate in the adjuvant treatment of patients with acute cerebral hemorrhage is better,which can effectively promote the recovery of neurological function,reduce the degree of cerebral edema,and improve the daily living ability of patients.

关键词

脑苷肌肽/七叶皂苷钠/急性脑出血/神经功能/日常生活能力

Key words

Cerebroside carnosine/Sodium aesculin/Acute cerebral hemorrhage/Neurological function/Daily living ability

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出版年

2024
医师在线

医师在线

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