富血小板纤维蛋白在牙周植骨手术中的临床观察
Clinical observation of platelet rich fibrin in periodontal bone graft surgery
雷朝锋 1王英博 1徐屹2
作者信息
- 1. 北京大学口腔医院第三门诊部,北京100191
- 2. 四川大学华西口腔医院牙周科,四川成都610041
- 折叠
摘要
目的:观察第二代血小板浓缩物富血小板纤维蛋白(PRF)和植骨材料联合应用在牙周植骨手术中的疗效.方法:纳入20名慢性牙周炎牙槽骨垂直吸收的患者,随机分为试验组和对照组(n=10).试验组植入PRF碎片和Bio-Oss骨粉混合物,再覆盖PRF膜,对照组仅植入Bio-Oss骨粉.分别于术前和术后6个月进行探诊深度(PD)、附着水平(AL)、Mazza出血指数(BI)检查,并进行骨内袋(IBD)影像学测量.结果:试验组和对照组术后PD、AL、BI、IBD均优于术前(P＜0.05).术后6个月,试验组PD、AL优于对照组(P＜0.05),BI、IBD两组间无统计学意义(P＞0.05).结论:治疗慢性牙周炎弧形骨缺损时,PRF配合Bio-Oss骨移植物的使用可以促进软、硬组织的愈合,而对于成骨作用有限.
Abstract
AIM:To observe the effects of second-generation platelet concentrated platelet-rich fibrin (PRF) on the periodontal tissue healing.METHODS:20 patients with intra-bony defects of chronic periodontitis were randomly divided into the test and the control groups (n =10).The patients in test group were treated with PRF and Bio-Oss combination,those in the control were treated with Bio-Oss alone.Probing depth (PD),attachment level (AL),Mazza bleeding index (BI) and radiographic measurements of intra-bony defect(IBD) were recorded at pre-surgical baseline and 6 months post-operatively.RESULTS:All the clinical and radiographic parameters of the 2 groups were improved after treatment(P ＜0.05).Mean PD reduction and AL gain in test group were more than in the control group(P ＜ 0.05).No statistically significant difference was found in BI and IBD between 2 groups.CONCLUSION:PRF combined with Bio-Oss bone graft may accelerate periodontal soft and hard tissue healing.
关键词
富血小板纤维蛋白(PRF)/慢性牙周炎/植骨术Key words
platelet-rich fibrin/chronic periodontitis/bone graft surgery引用本文复制引用
基金项目
四川省科技支撑项目(2015SZ0137)
出版年
2017
NETL
NSTL
维普
万方数据