可吸收镁基合金生物材料的研究现状
Research progress of magnesium based alloy biomaterials
史雨林 1王祥1
作者信息
- 1. 军事口腔医学国家重点实验室,口腔疾病国家临床医学研究中心,陕西省口腔疾病临床医学研究中心,第四军医大学口腔医院颌面外科,陕西西安710032
- 折叠
摘要
生物材料研究领域的前沿是可吸收材料,因为可吸收材料植入生物体内以后,能够在生物体内发生反应,并被吸收或排出体外.目前,在骨科相关领域植入的生物材料中,应用较多的可吸收生物材料是PLA(聚乳酸)和PGA(聚羟基乙酸),但这些高分子聚合材料具有降解产物呈酸性、容易引发炎症、力学性能较弱、负载能力较差等缺点.镁合金材料有非常好的力学物理性能,且对人体无毒,并能在体内经过腐蚀而逐步被降解,其作为一种有发展潜力的可吸收植入生物材料,很可能成为新一代颅颌面骨骼的内固定材料.本文就镁基合金作为可吸收植入材料的优点、研究现况及未来研究方向作一综述.
Abstract
Biodegradable biomaterials can be decomposed in vivo and the decomposed products can be absorbed or excreted by the organism.Widely used in bone implantation,the biodegradable materials are mainly polymers such as polylactic acid (PLA),polyglycolic acid (PGA),but the strength of these materials are generally low,it is difficult to bear large load,and the acidic degradation products,may lead to inflammation.Magnesium and its alloy not only has good mechanical properties,and non-toxic to humans,the corrosion can be gradually degraded in vivo,as a kind of promising biodegradable implant biomaterials magnesium is becoming increasingly popular and very likely to be a new generation of craniofacial fixation material.In this paper,the present research status of Mg based alloys is reviewed,and the advantages of Mg based alloys are proposed.
关键词
可吸收镁基合金生物材料Key words
absorbable magnesium based alloy biomaterials引用本文复制引用
出版年
2017
NETL
NSTL
维普
万方数据