抗菌牙科粘接剂在龋病治疗中的研究进展
Research progress of antibacterial dental adhesives in the treatment of caries
张灵俊 1章可可 1孙妍 1汪敏 1郑高哲 1潘乙怀 1余杰1
作者信息
- 1. 温州医科大学口腔医学院·附属口腔医院,浙江 温州 325000
- 折叠
摘要
牙科粘接剂在治疗细菌相关性疾病-龋齿过程中,发挥连接复合树脂及牙体组织的作用.通过对粘接剂进行改性,使其具备一定的抗菌功能,可有效抑制粘接界面细菌生长.本综述系统评估和总结了改性牙科粘接剂的各种策略,重点探讨包括金属及其化合物、季铵盐、天然抗菌药物、抗菌肽及载药系统等抗菌成分的应用前景.
Abstract
Dental adhesives play a crucial role in connecting composite resins to dental tissues during the treatment of bacteria-related diseases such as dental caries.By incorporating antimicrobial properties into modified dental adhesives,bacterial growth at the adhesive interface can be inhibited.This review systematically evaluates and summarizes various strategies of modified dental adhesives,focusing on the application prospects of antimicrobial agents including metals and their compounds,quaternary ammonium salts,natural antimicrobial agents,antimicrobial peptides,and drug delivery systems.
关键词
牙科粘接剂/龋病/抗菌/金属/季铵盐/抗菌肽/载药Key words
dental adhesive/dental caries/antimicrobial/metals/quaternary ammonium salts/antimicrobial peptides/drug delivery引用本文复制引用
基金项目
国家卫生健康委员会科研基金-浙江卫生健康重大科技计划项目(WKJ-ZJ-2214)
国家自然科学基金面上项目(82170950)
出版年
2024