摘要
偏头痛是神经科门诊最常见的疾病之一,其发病机制和药物治疗研究近年已取得新进展.本文介绍偏头痛的药物治疗包括急性发作的治疗及预防治疗.急性发作治疗的常用药物为非甾体类抗炎药、曲坦类、麦角碱类等.预防治疗的药物为三环类抗抑郁药、抗癫痫药、β-受体阻断剂、钙离子拮抗剂等.本文回顾这些药物的治疗作用和可能出现的不良反应,以期有益于临床安全合理用药.
Abstract
Migraine is one of the most common disorders in neurological clinic. New advances in pathogenesis and drug therapy for migraine have been obtained in recent years. This paper presents the drug therapy for migraine including treatment of acute attacks and preventive therapy. The common drugs used to treat acute migraine attacks are nonsteroidal non-inflammatory drugs, triptans, ergot alkaloids, etc. And the drugs used for preventive therapy are tricycle antidepressants, anticonvulsants, β-blockers, calcium channel blockers, etc. This article reviews the therapeutic actions and potential adverse reactions of these drugs in order to benefit the safe and rational drug use in clinical practice.
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