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中国老年人潜在不适当用药判断标准(2017年版)

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借鉴美国、加拿大、日本、法国、挪威、德国、韩国、奥地利、泰国等国家和中国台湾地区的老年人潜在不适当用药(PIM)标准,参考国家药品不良反应监测中心、全军药品不良反应监测中心和北京市药品不良反应监测中心的老年人严重不良反应所涉及药物情况以及北京市参与"医院处方分析合作项目"的22家医院60岁以上老年患者的用药数据,采用三轮德尔菲专家咨询法进行遴选,将遴选出的药物按照专家评分的高低分为高风险和低风险药物,并按照用药频度的高低分为 A级警示和B级警示药物,最终形成"中国老年人潜在不适当用药判断标准".中国标准包括两部分内容,第一部分为老年人PIM判断标准,包含神经系统用药、精神药物、解热镇痛抗炎抗风湿药物、心血管系统用药等13个大类72种/类药物,其中28种/类为高风险药物,44种/类为低风险药物;24种/类为A级警示药物,48种/类为B级警示药物;每种药物附有1~6个用药风险点.第二部分为老年人疾病状态下PIM标准,包含27种疾病状态下44种/类药物,其中25种疾病状态下35种/类药物为A级警示药物,9种疾病状态下9种/类药物为B级警示药物.
Criteria of potentially inappropriate medications for older adults in China
Based on the potentially inappropriate medication(PIM)criteria in older adults of the United States,Canada,Japan,France,Norway,Germany,South Korea,Austria,Thailand and Chinese Taiwan,and combined with the severe adverse drug reaction(ADR)data in the elderly of China National Center for ADR Monitoring,ADR monitoring center in the Chinese People′s Liberation Army,Beijing Center for ADR Monitoring and drug data of people over 60 years from Beijing 22 hospitals,3 rounds of Delphi expert consultation were made to accomplish the final criteria. The criteria was divided into high risk and low risk medications according to the experts evaluation and divided into A and B alert categories according to DDDs. Finally,criteria of potentially inappropriate medications for older adults in China was formed, including medication risk and medication risk under morbid state. A sum of 13 categories 72 medications or medication classes were selected in medication risk part,for example,neurologic medication,psychotropic medication,antipyretic,analgesic and anti-inflammatory medication and cardiovascular medication. The 72 medications were divided into 28 kinds of high risk and 44 kinds of low risk medications. The 72 medications were also divided into 24 kinds of preferred alert medications(A)and 48 kinds of routinely alert medications (B).PIM in the elderly under morbid state contained 44 medications or medication classes under 27 kinds of morbid states,in which 35 medications under 25 morbid states of preferred alert medications(A)and 9 medications under 9 morbid states of routinely alert medications(B).

Potentially inappropriate medication listAgedChina

中国老年保健医学研究会老年合理用药分会、中华医学会老年医学分会、中国药学会老年药学专业委员会、中国药理学会抗衰老与老年痴呆专业委员会、中国药理学会药源性疾病学专业委员会

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潜在不适当用药目录 老年人 中国

国家卫生部卫生行业科研专项北京市卫生系统高层次卫生技术人才培养计划北京市卫生系统高层次卫生技术人才培养计划

2010020112014-2-0142011-1-7

2018

药物不良反应杂志
中华医学会

药物不良反应杂志

CSTPCDCSCD
影响因子:0.667
ISSN:1008-5734
年,卷(期):2018.20(1)
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