1例71岁男性患者因器质性抑郁障碍口服盐酸文拉法辛缓释胶囊(文拉法辛缓释胶囊)75 mg/d,用药3 d 后出现牙龈轻微疼痛。因病情需要,将文拉法辛缓释胶囊剂量增至150 mg/d, 3 d后牙龈疼痛明显加重。停用文拉法辛缓释胶囊并给予口腔护理后4 d,患者牙龈疼痛症状消失。
Gingival pain due to venlafaxine hydrochloride sustained﹣release capsules
A 71﹣year﹣old male patient received venlafaxine hydrochloride sustained﹣release capsules 75 mg once daily orally for organic depressive disorder. On day 3 after medication,he developed mild gingival pain. The dose of venlafaxine hydrochloride sustained﹣release capsules was increased to 150 mg daily because of his condition. Three days later,his gingival pain aggravated significantly. Venlafaxine hydrochloride sustained﹣release capsules was stopped and oral care was given. On day 4 after the drug withdrawal,his gingival pain disappeared.