首页|A holistic visualization for quality of Chinese materia medica:Structural and metabolic visualization by magnetic resonance imaging

A holistic visualization for quality of Chinese materia medica:Structural and metabolic visualization by magnetic resonance imaging

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  • 国家科技期刊平台
  • NETL
  • NSTL
  • 万方数据
The quality of Chinese materia medica(CMM)is a challenging and focused topic in the modernization of traditional Chinese medicine(TCM).A profound comprehension of the morphology,structure,active constituents,and dynamic changes during the whole process of CMM growth is essential,which needs highly precise contemporary techniques for in-depth elucidation.Magnetic resonance imaging(MRI)is a cutting-edge tool integrating the benefits of both nuclear magnetic resonance(NMR)spectroscopy and imaging technology.With real-time,non-destructive,and in situ detection capabilities,MRI has been previously used for monitoring internal and external structures of plants alongside compounds during physiological processes in vivo.Here,factors involved in the holistic quality evaluation of CMMs were investigated.Given the applications of MRI in various plants,several representative CMMs were used as examples to demonstrate a methodology of quality visualization by MRI,embodying holistically monitoring the real-time macroscopic morphology,mesoscopic structure,and microscopic metabolites non-destructively in situ.Taken together,the review not only presents a pioneering application mode for uti-lizing MRI for CMM quality visualization but also holds promise for advancing the quality control and evaluation of CMMs.

Chinese materia medicaQualityStructure and metabolitesVisualizationMagnetic resonance imaging

Jing Wu、Kai Zhong、Hongyi Yang、Peiliang Zhang、Nianjun Yu、Weidong Chen、Na Zhang、Shuangying Gui、Lan Han、Daiyin Peng

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College of Pharmacy,Anhui University of Chinese Medicine,Hefei,230012,China

Department of Biomedical Engineering,Institute of Advanced Clinical Medicine,Peking University,Beijing,100191,China

Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei,230012,China

Ministry of Education-Anhui Joint Collaborative Innovation Center for Quality Improvement of Anhui Genuine Chinese Medicinal Materials,Anhui University of Chinese Medicine,Hefei,230012,China

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2024

10.1016/j.jpha.2024.101019

药物分析学报(英文)
西安交通大学

药物分析学报(英文)

影响因子：0.244
ISSN：2095-1779
年,卷(期)：2024.14(11)