药物流行病学杂志2024,Vol.33Issue(5) :500-507.DOI:10.12173/j.issn.1005-0698.202309036

聚桂醇注射液药物利用评价标准的建立与应用

Establishment and application of drug use evaluation standards for lauromacrogol

胡甜 贾莉 崔艳华 武蕊 张进华
药物流行病学杂志2024,Vol.33Issue(5) :500-507.DOI:10.12173/j.issn.1005-0698.202309036

聚桂醇注射液药物利用评价标准的建立与应用

Establishment and application of drug use evaluation standards for lauromacrogol

胡甜 1贾莉 2崔艳华 1武蕊 1张进华3
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作者信息

  • 1. 西安交通大学医学部附属三二○一医院药学部(陕西汉中 723000)
  • 2. 新疆维吾尔自治区人民医院药学部(乌鲁木齐 830000)
  • 3. 福建省妇幼保健院药剂科(福州 350001)
  • 折叠

摘要

目的 建立聚桂醇注射液的药物利用评价(DUE)标准,评价其临床使用情况,为临床合理应用聚桂醇提供参考.方法 以聚桂醇注射液药品说明书、相关指南和文献为基础,采用专家咨询法制定DUE标准细则,回顾性评价西安交通大学医学部附属三二○—医院2021年1月-2022年8月住院患者聚桂醇注射液的使用情况.结果 共纳入143份病历,聚桂醇注射液用药合理的病例有48例(33.57%).不合理用药主要表现为适应证不适宜(65.03%)和用法用量不适宜(1.40%),适应证不适宜主要为存在超说明书用药.结论 建立的聚桂醇注射液DUE标准细则对临床合理使用该药有一定的参考作用.该院聚桂醇注射液临床应用中尚存在一些问题,应制订相应的干预措施,优化其临床应用,促进合理用药.

Abstract

Objective To establish the drug use evaluation(DUE)standard of lauromacrogol,evaluate its clinical use,and provide a reference for rational clinical application.Methods Based on the drug instructions,related relevant guidelines and literature of lauromacrogol,the DUE standard was formulated through the expert consultation method.A retrospective study was conducted to evaluate the drug utilization of lauromacrogol in hospitalized patients in 3 201 Hospital of Xi'an Jiao tong University in Shaanxi province from January 2021 to August 2022.Results A total of 143 medical records were included,48(33.57%)of which fully met the evaluation criteria.Unreasonable use was mainly manifested as inappropriate indications(65.03%)and unsuitable usage and dosage(1.40%).The unreasonable indications are mainly due to the existence of off-label medication.Conclusion The established DUE standard of lauromacrogol has a certain reference effect on the rational use of lauromacrogol in clinical practice.Irrational usages still exists in the clinical application of lauromacrogol in the hospital,and interventions should be developed to optimize its clinical application and promote the rational drug use.

关键词

聚桂醇注射液/药物利用评价标准/合理用药/专家咨询法

Key words

Lauromacrogol/Drug use evaluation/Rational drug use/Expert consultation

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出版年

2024
药物流行病学杂志
中国药学会 武汉医药(集团)股份有限公司

药物流行病学杂志

CSTPCD
影响因子:0.746
ISSN:1005-0698
参考文献量19
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