Two female patients received insulin degludec and liraglutide injection and developed allergic urticaria after 1 day and 2 days respectively.The drug was discontinued and other insulin was used for glucose-lowering therapy,and anti-allergy treatment was administered with dexamethasone,cetirizine and topical cream,then two patients'symptoms gradually improved.The results of the association between the two adverse drug reactions and insulin degludec and liraglutide injection were"probably relevant".According to the domestic and foreign literature,there were rare reports of allergic urticaria in diabetic patients using insulin degludec and liraglutide injection.By analyzing the clinical characteristics of the two cases of adverse drug reactions,the role of clinical pharmacists in judging allergens and participating in the adjustment of hypoglycemic regimens is explored,which provides reference for individualized clinical medication and safe medication.
关键词
德谷胰岛素利拉鲁肽注射液/复方制剂/过敏性荨麻疹/药品不良反应
Key words
Insulin degludec and liraglutide injection/Compound preparation/Allergic urticaria/Adverse drug reaction
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