目的 分析替奈普酶的研究趋势和热点,为我国临床研究及合理用药提供参考依据.方法 全面检索Web of Science数据库自建库至2024年4月期间收录的替奈普酶研究相关文献,运用CiteSpace 6.1.R6软件进行作者、国家/地区、研究机构、关键词及参考文献共被引的可视化分析.结果 共有673篇文献纳入本研究,年度发文量整体呈上升趋势,近3年增长迅猛;美国、加拿大、澳大利亚是该领域发文量前3位的国家,发文量前10位的机构中,9所分别来自以上3个国家.研究热点分别为替奈普酶在急性心肌梗死和急性缺血性卒中患者中的疗效和安全性,近年来研究热点主要集中在急性缺血性卒中领域.结论 替奈普酶在急性缺血性卒中领域的应用是目前的研究热点,我国的研究水平较美国等发达国家仍存在差距.未来研究热点可能仍为替奈普酶在不同急性缺血性卒中类型患者中的应用,应重点关注.
Literature visualization analysis of research trends and hotspot evolution in teneteplase
Objective To analyze the research trends and hotspots of tenecteplase and provide a reference for clinical research and rational drug use in China.Methods A comprehensive search was conducted on tenecteplase studies in the Web of Science database from its inception to April 2024.CiteSpace 6.1.R6 software was used to analysis authors,countries/regions,research institutions,keywords,and co-cited references.Results A total of 673 articles were included in this study.The annual publication volume showed an overall upward trend,rapidly increasing in the past three years.The United States,Canada,and Australia were the top 3 countries in terms of publication volume in this field.Among the top 10 institutions in publication volume,9 were from above 3 countries.The research hotspots were the efficacy and safety of tenecteplase in patients with acute myocardial infarction and acute ischemic stroke.In recent years,research hotspots have mainly focused on the field of acute ischemic stroke.Conclusion The application of tenecteplase in the field of acute ischemic stroke is currently a research hotspot.However,there is still a gap between the research level in China and that in developed countries such as the United States.Future research hotspots may still focus on the application of tenecteplase in patients with different types of acute ischemic stroke,suggesting that scholars should pay close attention to this area.
万方数据
维普
