Analysis of the epidemiological characteristics and the prevention and control countermeasures of typhoid fever and paratyphoid fever in Guizhou Province from 2005 to 2020
Objective To analyze the epidemiological characteristics and the prevention and control countermeasures of typhoid fever and paratyphoid fever in Guizhou Province from 2005 to 2020,and to provide reference for the prevention and control of typhoid fever and paratyphoid fever.Methods Collection of data on typhoid fever and paratyphoid fever epidemics from The National Health Care Information System for Disease Control and Prevention,Guizhou Statistics Yearbook and Enteric Infectious Diseases Base Project and analyzed by descriptive epidemiological methods.Results Cumulative total of 22 746 cases of typhoid fever and paratyphoid fever were reported in Guizhou Province from 2005 to 2020,with 14 deaths and an average annual incidence rate of 3.93/100 000.The year with the highest incidence rate was 2005,at 15.21/100 000.The cities and counties(cities and districts)with the highest average annual incidence rates were Qianxi City,Nan Prefecture(8.40/100 000)and Xingyi City(15.08/100 000),with the incidence of the population dominated by peasants(7 835 cases accounting for 34.45%)and students(6 027 cases accounting for 27.29%)with the seasonal peak from May to October(15 826 cases accounting for 69.58%).The age of onset was predominantly 10 to 50 years old(17 758 cases accounting for 78.07%).A total of 24 outbreak epidemics and 939 cases were reported with an attack rate of 0.55%.A total of 1 883 strains were isolated,and Salmonella paratyphi A was predominant(74.14%).The drug resistance rates of Salmonella typhimurium and Salmonella paratyphi A to nalidixic acid were 26.45%and 93.18%,respectively.A total of 18 strategies and major actions for the prevention fever and control countermeasures of typhoid fever and paratyphoid fever played an important role in reducing the incidence rate of typhoid fever and paratyphoid fever.Conclusion The incidence rate of typhoid fever and paratyphoid fever in Guizhou Province shows a decreasing trend year by year.Previous prevention and control countermeasures and major actions have contributed significantly to the decline in the incidence rate of typhoid fever and paratyphoid fever.Previous effective countermeasures should be promoted in a targeted manner to effectively reduce the harm of typhoid fever and paratyphoid fever.
Typhoid fever and paratyphoid feverEpidemiological characteristicPrevention and control countermeasuresDescriptive epidemiologyDrug resistanceAnalysis