Objective To evaluate the differences in viral loads of confirmed cases and asymptomatic infections of COVID-19,and to provide scientific basis for research on COVID-19.Methods A descriptive epidemiological method was used to analyze the epidemiologic features and viral loads of swab samples from confirmed cases and asymptomatic infections of COVID-19 in a city from 2021 to 2022.Results A total of 121 cases were included,and 54.5％were confirmed cases.The ratio of male to female in confirmed cases was 2:1,and there was a significant difference in the COVID-19 cases between different genders(x2=7.496,P=0.006).And there was a significant difference in the COVID-19 cases in different age groups(x2=9.773,P=0.008).The difference in viral load was not statistically significant(Z=1.124,P=0.261)between the confirmed cases and asymptomatic infections.The difference in viral load was statistically significant(Z=2.147,P=0.033)between the confirmed cases and asymptomatic infections groups in the age group＞60 years old,and the median viral loads M(P25,P75)in the two groups were 12 466.5(1 861.3,168 323.6),and 3 256.3(972.8,42 043.3)copies/ml,respectively.Conclusion The difference in viral load is not statistically significant between confirmed cases and asymptomatic infections of COVID-19 but the level of viral load is significantly higher in confirmed cases than in asymptomatic infections in the age group ≥ 60 years,suggesting a relationship between viral load and disease severity among older age cases.
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