Objective To understand the epidemiological characteristics and etiological features of hand-foot-mouth disease(HFMD)in Xinjiang Production and Construction Corps(referred to as the Corps)from 2017 to 2022,and to provide a reference basis for scientific prevention and control.Methods The epidemiologic features of HFMD cases in the Corps were analyzed using descriptive epidemiological methods by obtaining information on HFMD cases data in the Corps from 2017 to 2022 through the Chinese Disease Prevention and Control Information System and etiologic data from the Corps Disease Prevention and Control Center.Results A total of 2 884 cases of HFMD were reported in the Corps from 2017 to 2022,with an average annual incidence rate of 15.64/100 000,and no serious or fatal cases.The incidence time showed a bimodal distribution pattern,with the highest peak in May to June and the second peak in September to October.The age of incidence was dominated by children under 5 years old,proportion was 83.91%.The male to female ratio was 1.41∶1,the difference was statistically significant between male and female incidence rate(x2=47.41,P<0.001).All 14 divisions of the Corps had incidence,and the incidence rate was significantly higher in northern Xinjiang Area(10 divisions,with an annual average incidence rate of 86.63/100 000)than that in southern Xinjiang Area(4 divisions,with an annual average incidence rate of 42.84/100 000),the difference was statistically significant(x2=192.38,P<0.001).The etiological surveillance results showed that the Corps was dominated by other Enteroviruses and Coxsackievirus A16(Cox A16)type,proportion was 85.00%.Enterovirus 71(EV 71)type was an overall decreasing trend but increasing from 2021,and other Enteroviruses were generally fluctuating above and below 50.00%.Conclusion The epidemic of HFMD in the Corps has obvious regional,temporal and population distribution.Prevention and control measures should be targeted to carry out to reduce the incidence.In response to changes in the etiological spectrum,other Enteroviruses are further typed to clarify the dominant pathogens of the onset of HFMD in the Corps to provide support for the prevention and control of the epidemic.
Xinjiang Production and Construction CorpsHand-foot-mouth diseaseEpidemiological characteristicEtiologyEnterovirusPrevention and control measuresAnalysis