首页|2017-2022年新疆生产建设兵团手足口病流行特征及病原学分析

2017-2022年新疆生产建设兵团手足口病流行特征及病原学分析

Epidemiological characteristics and etiological analysis of hand-foot-mouth disease in Xinjiang Production and Construction Corps from 2017 to 2022

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目的 了解2017-2022年新疆生产建设兵团(简称"兵团")手足口病流行特征和病原学特点,为科学防控提供参考依据.方法 通过中国疾病预防控制信息系统获取2017-2022年兵团手足口病病例资料,从兵团疾病预防控制中心获取病原学资料,采用描述性流行病学方法对兵团手足口病病例流行病学特征进行分析.结果 2017-2022年兵团共报告手足口病2 884例,年均发病率为15.64/10万,无重症和死亡病例;发病时间呈双峰分布,5~6月为最高峰,9~10月为次高峰;发病年龄以5岁以下儿童为主,构成比为83.91%,男女比例为1.41∶1,男女发病率差异有统计学意义(x2=47.41,P<0.001);兵团14个师均有发病,北疆地区发病率(10个师,年均发病率为86.63/10万)明显高于南疆地区(4个师,年均发病率为42.84/10万),差异有统计学意义(x2=192.38,P<0.001).病原学监测结果显示,兵团手足口病以其他肠道病毒和柯萨奇病毒A16(Coxsackievirus A16,Cox A16)型为主,构成比为85.00%,肠道病毒71(Enterovirus 71,EV 71)型整体处于下降趋势,但从2021年起有所上升,其他肠道病毒总体在50.00%上下波动.结论 兵团手足口病的流行有明显的地区、时间、人群分布特点,应有针对性开展防控措施,降低发病率.针对病原谱变化,对其他肠道病毒进一步分型,明确兵团手足口病发病优势病原,为疫情防控提供支持.
Objective To understand the epidemiological characteristics and etiological features of hand-foot-mouth disease(HFMD)in Xinjiang Production and Construction Corps(referred to as the Corps)from 2017 to 2022,and to provide a reference basis for scientific prevention and control.Methods The epidemiologic features of HFMD cases in the Corps were analyzed using descriptive epidemiological methods by obtaining information on HFMD cases data in the Corps from 2017 to 2022 through the Chinese Disease Prevention and Control Information System and etiologic data from the Corps Disease Prevention and Control Center.Results A total of 2 884 cases of HFMD were reported in the Corps from 2017 to 2022,with an average annual incidence rate of 15.64/100 000,and no serious or fatal cases.The incidence time showed a bimodal distribution pattern,with the highest peak in May to June and the second peak in September to October.The age of incidence was dominated by children under 5 years old,proportion was 83.91%.The male to female ratio was 1.41∶1,the difference was statistically significant between male and female incidence rate(x2=47.41,P<0.001).All 14 divisions of the Corps had incidence,and the incidence rate was significantly higher in northern Xinjiang Area(10 divisions,with an annual average incidence rate of 86.63/100 000)than that in southern Xinjiang Area(4 divisions,with an annual average incidence rate of 42.84/100 000),the difference was statistically significant(x2=192.38,P<0.001).The etiological surveillance results showed that the Corps was dominated by other Enteroviruses and Coxsackievirus A16(Cox A16)type,proportion was 85.00%.Enterovirus 71(EV 71)type was an overall decreasing trend but increasing from 2021,and other Enteroviruses were generally fluctuating above and below 50.00%.Conclusion The epidemic of HFMD in the Corps has obvious regional,temporal and population distribution.Prevention and control measures should be targeted to carry out to reduce the incidence.In response to changes in the etiological spectrum,other Enteroviruses are further typed to clarify the dominant pathogens of the onset of HFMD in the Corps to provide support for the prevention and control of the epidemic.

Xinjiang Production and Construction CorpsHand-foot-mouth diseaseEpidemiological characteristicEtiologyEnterovirusPrevention and control measuresAnalysis

赵倩、成彦彪、于亚乐、郭景霞、何尧、王童敏

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新疆生产建设兵团疾病预防控制中心,新疆维吾尔自治区乌鲁木齐 830002

新疆生产建设兵团 手足口病 流行特征 病原学 肠道病毒 防控措施 分析

新疆生产建设兵团疾控中心项目

BTCDCKY202203

2024

医学动物防制
中国民主促进会河北省委员会

医学动物防制

CSTPCD
影响因子:0.553
ISSN:1003-6245
年,卷(期):2024.40(5)
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