分子对接技术在药物设计学教学中的应用
Application of Molecular Docking Technology in Teaching Drug Design
赵宏 1高琪 1宋琳琳 1王宇亮 1王丽红 1沈宇 1平洋 1马常友1
作者信息
- 1. 佳木斯大学药学院(佳木斯 154007)
- 折叠
摘要
药物设计学是一门涉及新药研究开发程序、方法手段和要求的新兴学科,涵盖多门学科知识,在新药研发类综合型人才培养的知识体系中具有重要地位.本文采用模拟实操教学法,以人参皂苷抗阿尔茨海默病为例,将计算机辅助药物设计中的分子对接技术应用于实战演练,以提升理论教学的效果,加深学生对课堂理论知识的理解,提升学生的创新思维能力和实践运用能力.
Abstract
Drug design is an emerging discipline that involves the processes,methodologies,and require-ments of new drug research and development,encompassing knowledge from multiple disciplines and hold-ing a significant position in the education system for training comprehensive talent in new drug research and development.This paper adopts a simulated practical operation teaching method,taking the use of ginsenosides in the treatment of Alzheimer's disease as an example,to apply molecular docking techniques from computer-aided drug design in practical exercises.This enhances the effectiveness of theoretical teaching,deepens students'understanding of classroom theoretical knowledge,and improves students'innovative thinking and practical application skills.
关键词
药物设计学/分子对接技术/模拟实战式/人参皂苷/阿尔茨海默病Key words
drug design/molecular docking technology/simulated practical teaching/ginsenoside/Alzheimer's disease引用本文复制引用
基金项目
黑龙江省高等教育教学改革研究项目(重点委托项目)(SJGZ20190061)
黑龙江省高等教育教学改革研究项目(SJ-GY20210865)
黑龙江省特色领域卓越研究生培养建设项目(HLJYJSZLTSGC-ZYYJSPY-2022-037)
出版年
2024
NETL
NSTL
万方数据