摘要
目的：观察不同浓度他克莫司乳膏治疗阴囊慢性湿疹的疗效和安全性。方法阴囊慢性湿疹患者80例，随机分为两组，每组40例，分别采用0．1％和0．03％他克莫司乳膏治疗，早晚各1次，2周后评价临床疗效以及治疗后的不良反应。结果两组有效率分别为92．5％、55．0％，差异有显著统计学意义（χ2＝14．53，P＜0．001）；治疗后两组的不良反应发生率分别为12．5％、5．0％，差异无统计学意义（χ2＝1．41，P＞0．05）。结论0．1％他克莫司乳膏治疗阴囊慢性湿疹疗效明显优于0．03％他克莫司乳膏，且不良反应少，值得临床推广应用。
Abstract
Objective:Evaluation of the ef icacy and safety of dif erent concentrations tarcrolimus cream for the chroniceczema of scrotum.Methods:Random divide 80 cases into the two group .40 cases of each group.Twice a day by 0.1%and 0.03%tarcrolimus cream respectively.Evaluate clinical curative ef icacy after 2 weeks and safety.Results:The ef ective rate of 0.1%tarcrolimus cream group is 92.5%,0.03%tarcrolimus cream group is 55.0%.The diference was statistical y significant(χ2=14.53,P<0.001);The incidence of adverse reactions of the two groupswere12.5%,5%respectively.Thediferencewasnotstatisticalysignificant(χ2=1.41,P>0.05);Conclusion:0.1%tacrolimuscreaminthetreatmentofchroniceczemaofscrotumis obviously bet er than that of 0.03% tacrolimus cream,and less adverse reaction,it is worthy of clinical application.
NETL
NSTL
维普
万方数据