摘要
目的:了解药品不良反应(ADR)发生的特点与规律,促进临床合理用药。方法收集2011年我院64例ADR报告,分别从患者性别、年龄、给药途径、所用药物、引发ADR的药品种类及发生率、ADR涉及的系统及临床表现等进行统计分析。结果64例报告中,60岁以上患者ADR发生率高于其它年龄段(22例,占34.4%),从给药途径看,静脉滴注较其它给药途径更易发生ADR(62例,占96.88%),从药物分类看,抗感染药引发ADR的比例最高(43例,占67.19%)。结论应高度重视ADR工作,完善相关报告分析制度,确保用药安全。
Abstract
Objective To investigate the characteristics and general features of adverse drug reactions (ADR)occurred in our hospital for reference of clinical rational drug administration. Methods 64 ADR cases col ected in our hospital in 2011 were analyzed statistical y in respect of patients’gender,age,route of administration,variety of drugs and their percentages of inducing ADR,system related to ADR and clinical manifestations etc.Results Looking from the perspective of gender,there was no sharp dif erence between male and female.Looking from the perspec-tive of age,the incidence of patients over 60 years old was higher than other age groups (22 cases,34.4%).Looking from the perspective of route of administration,the ADR in intravenously administered drugs was more easily induced compared with other routes of administration (62 cases,96.88%).Looking from the perspective of variety of drugs,the ratio of the ADR induced by antimicrobials was the highest (43 cases,67.19%).Conclusion ADR monitoring should be highly emphasized and related report analysis system should be improved to ensure clinical rational drug administration.