纳洛酮氨茶碱联合应用治疗早产儿原发性呼吸暂停（AOP）的疗效观察
陈静1
作者信息
- 1. 资阳市第一人民医院儿科 四川 资阳 641300
- 折叠
摘要
目的：观察纳洛酮氨茶碱联合应用治疗早产儿原发性呼吸暂停（AOP）的疗效。方法：将我院儿科2013年5月～2014年5月收治的原发性呼吸暂停早产儿60例随机分为治疗组30例，对照组30例。两组均在抗感染支持及对症治疗基础上使用氨茶碱注射液治疗呼吸暂停，首次负荷量5mg／kg 静注，12小时后给予维持量2mg／kg，每12小时给药1次稀释后静注；治疗组加用纳洛酮注射液，首次负荷是为0．1mg／kg 静注，1小时后按0．01mg／（kg·小时），经微泵持续静注，每日总量不超过0．4mg／kg。结果：治疗组疗效明显优于对照组，两组有非常显着差异 P ＜0．01。结论：纳洛酮氨茶碱联合应用治疗早产儿原发性呼吸暂停疗效优于单用氨茶碱。
Abstract
Objective:To observe the ef ect of combined application of naloxone and aminophyl ine in treatment of primary apnea of premature infants (AOP)ef ect.Methods:in our hospital in 2013 May ~2014 year pediatrics in May were primary apnea of premature infants 60 cases were randomly divided into treatment group 30 cases,control group 30 cases.In two groups of anti infection and support therapy treatment on the basis of using Aminophyiline Injection treatment of apnea,first load 5mg/kg intravenous injection,after 12 hours to maintain the amount of 2mg/kg,administered every 12 hours for 1 times diluted intravenous injection;treatment group was added with naloxone injection,the first load is 0.1mg/kg intravenous injection,1 hours after the according to 0.01mg/(kg hours),the micro pump continuous intravenous injection,the daily amount of not more than 0.4mg/kg.Results:the curative ef ect of the treatment group was sig-nificantly bet er than the control group,the two groups have a very significant dif erence in P <0.01.Conclusion:naloxone and aminophyl ine on primary apnea of premature infants curative ef ect is bet er than that of aminophyl ine.
关键词
纳洛酮氨茶碱/治疗/早产儿原发性呼吸暂停/疗效观察Key words
aminophyl ine treatment/naloxone/primary apnea of premature infants/curative ef ect observation引用本文复制引用
出版年
2015
NETL
NSTL
维普
万方数据