尿微量白蛋白(MAlb)和尿β2-微球蛋白(β2-MG)在糖尿病肾病(DN)早期诊断中的意义
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作者信息
- 1. 内蒙古自治区满洲里市中蒙医院 内蒙古 满洲里 021400
- 折叠
摘要
目的:探讨尿微量白蛋白(MAlb)和尿β2-微球蛋白(β2-MG)在糖尿病肾病(DN)早期诊断中的意义。方法:采用放射免疫法对25例健康者和78例糖尿病患者进行24h 尿 MAlb 及β2-MG 定量测定。结果:随着病程的发展,24h 尿 MAlb 排泄量和24h 尿β2-MG 排泄量逐渐增高。在糖尿病(DM)患者中24h 尿 MAlb 排泄量与24h 尿β2-MG 排泄量成正相关(r =0.477,P <0.01)。结论:24h 尿 MAlb 排泄量和24h 尿β2-MG 排泄量联检有助于全面评估 DM的肾脏损害,早期诊断 DN。
Abstract
Objective:To evaluate the value of urinary micro albumin(MAlb)and β2 -Microglobulin(β2 -MG)in the early diagnosis of diabetic nephropathy (DN)〃 Methods:Both 24 hours urinary MAlb and β2 -MG excretion amount were measured from 64 diabetic patients and 32 normal people as control group respectively by radio immunoassay〃 Results:It showed that both 24 hours urinary MAlb and B2 -MG excretion amounts were increased gradual y when the disease development,24 hours urinary MAlb excretion amount in patients with DMshowed a significant positive correlation 24 hours urinary with β2 -MG excretion amount(r =0.477,P <0.01)〃Conclusion:Combined 24 hours urinary MAlb with urinary β2 -MG excretion amount may be conducive to evaluate the renal damage in DMand to diagnose DN early〃
关键词
糖尿病肾病微量白蛋白/β2/-微球蛋白Key words
Diabetic nephropathyMicroalbumin/β2 -Microglobulin引用本文复制引用
出版年
2015