Research Status of Erythropoietin and its Derivative in Ischemia/Reperfusion Injury
Inrecentyears,domesticandforeignresearchersarebecomingmoreandmoreatentiontoerythropoietin(EPO)anditsderivativeinnon-erythropoieticfunction.Scholars found that EPO and its derivative had obvious ef ects of protecting vital organs,such as at enuating apoptosis,anti-inflammatory,reducing oxidative stress,improving organic function etc.This ar-ticle summarizes the study of related mechanism of erythropoietin and its derivative in ischemia/reperfusion injury,ef ect of doseand drug administration time,ef ectiveness evaluation and clinical application,and the prospect of the application is glimpsed as wel .
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