摘要
目的:观察米索前列醇与催产素联合应用预防剖宫产产后出血的临床疗效。方法:124例拟行剖宫产手术的产妇被编号并随机分为两组,各组62例。入选对照组者单纯应用催产素,入选观察组者应用米索前列醇与催产素,对比两组产妇产后出血量、产后出血发生率及不良反应发生率。结果:观察组产妇产后2h 出血量(158.42±26.73)ml、产后24h 出血量(262.47±56.19)ml 较对照组明显减少,产后出血发生率(3.23)%较对照组明显降低,差异具有统计学意义(P <0.05)。两组不良反应发生率无显著性差异(P >0.05)。结论:米索前列醇与催产素联合应用能够有效降低剖宫产术后出血的发生率,减少产妇产后出血量,且不良反应较少,安全可靠。
Abstract
Objective:To observe the clinical ef icacy of misoprostol combined with oxytocin in preventing postpartum hemorrhage.Methods:124 cases undergoing cesarean section puer-pera were numbered and randomly divided into two groups,each group of 62 cases.Selected in the control group were given simply oxytocin,the observation group were given misoprostol and ox-ytocin,compared two groups of postpartum hemorrhage,postpartum hemorrhage rate and incidence of adverse reactions.Results:The 2h postpartum hemorrhage (158.42 ±26.73)ml,24h postpartum hemorrhage (262.47 ±56.19)ml were significantly reduced compared with the control group,the incidence of postpartum hemorrhage (3.23)%,significantly lower than the con-trol group,the dif erence was statistical y significance (P <0.05).Groups incidence of adverse reactions was no significant dif erence (P >0.05).Conclusion:misoprostol and oxytocin in combination can ef ectively reduce the incidence of hemorrhage after cesarean section to reduce postpartum bleeding,and fewer side ef ects,safe and reliable.