Exploration on the Relationship between Multi-Component and Multi-Pharmaceutical Efficacy of Treatment of Acute Pan-creatitis with Dachengqi Decoction Based on Orthogonal Partial Least Squares
Exploration on the Relationship between Multi-Component and Multi-Pharmaceutical Efficacy of Treatment of Acute Pan-creatitis with Dachengqi Decoction Based on Orthogonal Partial Least Squares
Purpose/Significance To analyze the experimental data of Dachengqi Decoction in treating acute pancreatitis and confirm the relationship between multi-component and multi-pharmaceutical efficacy.Method/Process The paper uses orthogonal partial least squares(OPLS)regression to analyze the relationship between the Chinese medicine compatibility,the Chinese medicine components of the decoction liquid,the Chinese medicine components of the blood and the pharmaceutical efficacy indicators respectively.Result/Con-clusion There are one-to-many,many-to-one,and many-to-many relationships between the Chinese medicine compatibility and the pharmaceutical efficacy indicators,the Chinese medicine components of the decoction liquid and the pharmaceutical efficacy indica-tors,the Chinese medicine components of the blood and the pharmaceutical efficacy indicators.The experimental results indicate that the treatment of acute pancreatitis with Dachengqi Decoction presents the characteristics of multiple components and multiple pharmaceutical efficacy.
关键词
中药成分/药效指标/正交偏最小二乘法
Key words
traditional Chinese medicine components/pharmaceutical efficacy indicators/orthogonal partial least squares