医学信息学杂志2024,Vol.45Issue(11) :43-49.DOI:10.3969/j.issn.1673-6036.2024.11.007

基于改进关联规则与logistic回归算法集成的2型糖尿病中医证型鉴别研究

Study on TCM Syndromes Differentiation of Type 2 Diabetes Based on the Integration of Improved Association Rules and Lo-gistic Regression Algorithm

刘红萍 杨杰 庞国明 邢颖 李鹏辉 吴敏 温宵宵 李洪皎 文天才
医学信息学杂志2024,Vol.45Issue(11) :43-49.DOI:10.3969/j.issn.1673-6036.2024.11.007

基于改进关联规则与logistic回归算法集成的2型糖尿病中医证型鉴别研究

Study on TCM Syndromes Differentiation of Type 2 Diabetes Based on the Integration of Improved Association Rules and Lo-gistic Regression Algorithm

刘红萍 1杨杰 1庞国明 2邢颖 1李鹏辉 2吴敏 1温宵宵 1李洪皎 3文天才1
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作者信息

  • 1. 中国中医科学院中医药信息研究所 北京 100700;中国中医科学院中医药数据中心 北京 100700
  • 2. 开封市中医院 开封 475000
  • 3. 中国中医科学院中医临床基础医学研究所 北京 100700
  • 折叠

摘要

目的/意义 分析2型糖尿病患者中西医特征间的多维交互关系及其对中医辨证的影响.方法/过程 基于真实世界电子病历数据,改进传统关联规则算法,增加尊重度指标,筛选重要的中医证型作为因变量进入logistic回归算法,分析中西医临床指标与中医证型的关联.结果/结论 基于688例患者得到关联规则112条,其中包含中医证型的有12条.中土壅滞证与超重/肥胖的关联规则尊重度最大,且超重/肥胖患者的中土壅滞证患病率更高.中土壅滞证、合并周围神经病变、合并高血压与超重/肥胖的关联性较强.合并糖尿病肾病患者出现气阴两虚证的可能性更大.

Abstract

Purpose/Significance To analyze the multidimensional interaction between the characteristics of traditional Chinese and western medicine in patients with type 2 diabetes mellitus and its influence on traditional Chinese medicine(TCM)syndrome differentia-tion.Method/Process Based on the real-world electronic medical record(EMR)data,the traditional association rule algorithm is im-proved,and the important TCM syndromes are screened out as dependent variables by increasing the respect index,and the logistic regres-sion algorithm is used to explore the influence of traditional Chinese and western medicine indexes on TCM syndromes.Result/Conclusion Based on 688 patients,112 association rules are obtained,of which 12 includes TCM syndromes.The respect of association rules between middle-earth stagnation syndrome and overweight/obesity is the highest,moreover,overweight/obesity patients have a higher prevalence rate of middle-earth stagnation syndrome.There is a strong correlation between middle-earth stagnation syndrome,peripheral neuropathy or hypertension and overweight/obesity.Patients with diabetic nephropathy are more likely to have qi and yin deficiency syndrome.

关键词

2型糖尿病/中西医特征/中医证型/关联规则/真实世界研究

Key words

type 2 diabetes mellitus/characteristics of traditional Chinese and western medicine/traditional Chinese medicine(TCM)syndrome types/association rules/real world study

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出版年

2024
医学信息学杂志
中国医学科学院

医学信息学杂志

CSTPCD
影响因子:1.348
ISSN:1673-6036
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