医学信息学杂志2024,Vol.45Issue(12) :69-74.DOI:10.3969/j.issn.1673-6036.2024.12.011

基于人工智能的儿童抗菌药物超适应证评估系统设计与应用

Design and Application of the Children's Antibacterial Drugs Off-label Use Assessment System Based on Artificial Intelligence

陆昕玥 朱珠 赵永根 朱正怡 陈凌栋 俞刚
医学信息学杂志2024,Vol.45Issue(12) :69-74.DOI:10.3969/j.issn.1673-6036.2024.12.011

基于人工智能的儿童抗菌药物超适应证评估系统设计与应用

Design and Application of the Children's Antibacterial Drugs Off-label Use Assessment System Based on Artificial Intelligence

陆昕玥 1朱珠 1赵永根 1朱正怡 2陈凌栋 1俞刚1
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作者信息

  • 1. 浙江大学医学院附属儿童医院数据信息部 杭州 310052;浙江-芬兰儿童健康人工智能联合实验室 杭州 310052;国家儿童健康与疾病临床医学研究中心儿童健康医工信交叉研究中心 杭州 310052
  • 2. 浙江大学医学院附属儿童医院药剂科 杭州 310052
  • 折叠

摘要

目的/意义建立抗菌药物超适应证评估系统,提升儿童抗菌药物管理水平.方法/过程基于自然语言处理技术,对电子病历等非结构化数据进行后结构化处理;基于深度学习算法模型和用药规则知识库,分析患儿用药特征数据,构建抗菌药物超适应证评估模型;设计并实现评估系统,为医生提供较准确的处方智能审核提示.结果/结论该系统对37 372例患儿进行用药评估,为临床医生提供了有效的用药决策参考,满足了医院对儿童抗菌药物超适应证管理的需求.

Abstract

Purpose/Significance To establish the off-label evaluation system of antibacterial drugs and to improve the management level of antibacterial drugs for children.Method/Process Based on natural language processing(NLP)technology,post-structured processing of unstructured data such as electronic medical record(EMR)is carried out.Based on the deep learning algorithm model and medication rule knowledge base,the medication characteristics data of children are analyzed,and an evaluation model for off-label use of antibacterial drugs is constructed.Additionally,the off-label evaluation system of antibacterial drugs is designed and implemented,providing physicians with accurate intelligent prompts for reviewing antimicrobial prescriptions.Result/Conclusion This system evaluates the antibacterial drugs use of 37 372 children,provides effective references for clinicians to make decisions antibacterial drugs,and meets the requirements of hospitals for off-label administration of children's antibacterial drugs.

关键词

抗菌药物管理/超适应证用药/人工智能/临床辅助决策系统

Key words

antibacterial drugs management/off-label drug use/artificial intelligence(AI)/clinical decision support system(CDSS)

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出版年

2024
医学信息学杂志
中国医学科学院

医学信息学杂志

CSTPCD
影响因子:1.348
ISSN:1673-6036
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