首页|Cardiac resident macrophages:Spatiotemporal distribution,development,physiological functions,and their translational potential on cardiac diseases

Cardiac resident macrophages:Spatiotemporal distribution,development,physiological functions,and their translational potential on cardiac diseases

扫码查看
原文链接
  • NETL
  • NSTL
  • 万方数据
Cardiac resident macrophages(CRMs)are the main population of cardiac immune cells.The role of these cells in regeneration,functional remodeling,and repair after cardiac injury is always the focus of research.However,in recent years,their dynamic changes and contributions in physiological states have a significant attention.CRMs have specific phenotypes and functions in different cardiac chambers or locations of the heart and at different stages.They further show specific differentiation and development processes.The present review will summarize the new progress about the spatiotem-poral distribution,potential developmental regulation,and their roles in cardiac development and aging as well as the translational potential of CRMs on cardiac diseases.Of course,the research tools for CRMs,their respective advantages and disadvantages,and key issues on CRMs will further be discussed.

Cardiac resident macrophagesSpatiotemporal distributionCardiac developmentCardiac homeostasisPhysiological functionsResearch toolsClinical translationTranscriptional characteristics

Jing Jin、Yurou Wang、Yueqin Liu、Subrata Chakrabarti、Zhaoliang Su

展开 >

International Genome Center,Jiangsu University,Zhenjiang 212013,China

Institute for Medical Immunology,Jiangsu University,Zhenjiang 212013,China

Center Laboratory,the Fourth People's Hospital of Zhenjiang,Zhenjiang 212008,China

Department of Pathology and Laboratory Medicine,Western University,London,Ontario N6A 5C1,Canada

展开 >

国家自然科学基金国家自然科学基金Six Talent Peaks Project in Jiangsu Province,ChinaInternational Cooperation from Jiangsu Province,ChinaKey Funds from the Health Commission of Jiangsu Province,ChinaSocial Development Foundation of Zhenjiang,China

32370984821019142019-WSN-122BX2019100ZD2021009SH2022060

2024

10.1016/j.apsb.2023.12.018

药学学报(英文版)

药学学报(英文版)

CSTPCD
ISSN：
年,卷(期)：2024.14(4)
  • 103