Pioneering integration of combinatorial chemistry and machine learning to accelerate the development of tailored LNPs for mRNA delivery

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原文链接

万方数据
维普

外文关键词：

Ionizable lipidCombinatorial chemistryHigh-throughput synthesisLipid nanoparticlesHigh-throughput screeningMachine learningmRNA deliverymRNA therapeutics

作者：

Xi He、Pingyu Wang、Linbo Qing、Xiangrong Song

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作者单位：

Department of Critical Care Medicine,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University,Chengdu 610041 China

College of Electronics and Information Engineering,Sichuan University,Chengdu 610065,China

出版年：

2024

DOI：

10.1016/j.apsb.2024.08.032

药学学报(英文版)

CSTPCD

ISSN：

年,卷(期)：2024.14(11)