Correlation between HbA1c and Other Risk Factors in Cerebral Infarction Patients with Diabetes Mellitus
Objective To explore the correlation between glycated hemoglobin(HbA1 c)and other risk factors in cerebral infarction(CI)patients with diabetes mellitus(DM),to observe the correlation between HbA1e and its related indicators and neurological deficits.Methods A total of 1012 patients with first-onset CI combined with DM who were treated in the Department of Acupuncture and Moxi-bustion,the First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine from August 2012 to August 2022 were retro-spectively collected.They were divided into normal group(n=207)and elevated group(n=805)based on the HbA1c values measured at admission.The variation characteristics of the two groups of data parameters were compared.Multiple linear regression analysis and bi-nary Logistic regression analysis were used to screen the influencing factors of HbA1c level change in CI patients with DM,and to explore the correlation between the influencing factors and the severity of the disease.Results There were no significant differences in smoking history,coronary heart disease history,age,drinking history,gender,and hypertension history between the two groups(P＞0.05);there were significant differences in HbA1c,blood glucose(Glu),blood platelet(PLT),fibrinogen(Fb),homocysteine(HCY)and triglycer-ide(TG)between the two groups(P＜0.05);a total of 5 indexes were found to be related to the change of HbA1c level:Glu,PLT,Fb,HCY and TG.Multiple linear regression analysis showed that Glu,HCY and Fb were the influencing factors of HbA1c.The results of bi-nary Logistic regression analysis showed that Glu,HbA1c and Fb were the influencing factors of moderate and severe neurological deficits.Conclusion The HbA1c level in patients with CI combined with DM is significantly correlated with the changes of Glu,PLT,Fb,HCY and TG levels.
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