Investigation on the Influence of Allergic Rhinitis on SARS-CoV-2 Infection
Objective To explore whether suffering from allergic rhinitis(AR)would affect the rate and severity of severe acute re-spiratory syndrome coronavirus 2(SARS-CoV-2)infection.Methods A single-center retrospective questionnaire survey was con-ducted in AR patients and non-AR controls.The questionnaire includes the basic demographic characteristics of the respondents,wheth-er they had SARS-CoV-2 infection,the severity score of infection symptoms,and the risk factors that may affect the severity of infec-tion.Statistical analysis was conducted after completing the questionnaire.Results The infection rate of SARS-CoV-2 was 83.9%(162/193)in AR group and 86.0%(166/193)in control group,there was no significant difference between the two groups(P>0.05).There was no significant difference in the total severity score of infection symptoms between AR group[10(7,14)]and control group[10(6,13)](P>0.05).The symptoms of suffocation,vomiting and diarrhea in AR patients infected with SARS-CoV-2 were more severe than those in controls.The total severity score of SARS-CoV-2 infection symptoms in male AR patients was 8.0(5.8,11.0),which was significantly lower than that in female AR patients[10.5(8.0,14.0)],and the difference was statistically significant(P=0.002).Conclusion There was no significant difference in the infection rate and severity between AR patients and controls in the mild SARS-CoV-2 infected subjects of this study,but gender might affect the severity of infection symptoms in AR patients.