首页|云南地区不同民族人群糖化血红蛋白水平分布情况分析

云南地区不同民族人群糖化血红蛋白水平分布情况分析

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目的 探讨云南地区汉族、彝族、哈尼族和傣族不同性别及年龄段间糖化血红蛋白(glycosylated hemoglobin,HbA1c)水平的分布情况.方法 采集云南省玉溪市汉族普通人群16363例,彝族普通人群950例,哈尼族普通人群830例,傣族普通人群1044例.4个民族按年龄段分成5组(25~39岁、40~49岁、50~59岁、60~69岁、≥70岁).分析比较4个民族不同性别及不同年龄组HbA1c的分布情况.结果 4个民族中,彝族HbA1c总体水平最高,其次为哈尼族、汉族,傣族最低.HbA1c总体水平比较差异有统计学意义(P<0.05),其中组间两两比较,除彝族与哈尼族差异无统计学意义外,其余组间差异均有统计学意义(P<0.05).除彝族外,汉族、哈尼族、傣族3个民族的不同性别间HbA1c水平比较差异有统计学意义(P<0.05).趋势上,汉族男性和女性HbA1c水平随年龄增长而升高,其他3个少数民族HbA1c水平均存在拐点,4个民族在60~69岁这个年龄段HbA1c水平女性均高于男性.结论 4个民族HbA1c总体水平存在差异,各民族不同性别间随年龄变化的分布趋势有所不同.
Distribution of Glycosylated Hemoglobin in Different Ethnic Groups in Yunnan Province
Objective To investigate the distribution of glycosylated hemoglobin(HbA1c)levels between different genders and ages of Han,Yi,Hani and Dai ethnic groups in Yunnan province.Methods A total of 16363 cases of Han nationality,950 cases of Yi na-tionality,830 cases of Hani nationality and 1044 cases of Dai nationality were collected from Yuxi city,Yunnan province.The four ethnic groups were divided into 5 groups according to age(25-39 years,40-49 years,50-59 years,60-69 years,≥70 years).The distri-bution of HbA1c in different genders and age groups of four ethnic groups were analyzed and compared.Results Among the four ethnic groups,the Yi nationality had the highest HbA1c level,followed by Hani nationality,Han nationality,and Dai nationality had the lowest HbA1c level.There were significant differences in the overall level of HbA1c(P<0.05).Pairwise comparison between groups showed significant differences except for Yi and Hani nationality(P<0.05).Except for Yi nationality,there were significant differences in HbA1c levels among different genders of Han nationality,Hani nationality and Dai nationality(P<0.05).In terms of trend,the HbA1c levels of Han males and females increased with age,while the HbA1c levels of the other three ethnic minorities all showed an inflection point.The HbA1c levels of the four ethnic groups were higher in females than in males at the age of 60-69 years.Conclusion There are differences in the overall level of HbA1c among the four ethnic groups,and the distribution trend with age is different among different genders in each ethnic group.

Glycosylated hemoglobinEthnicityGenderAge

张春婷、谢凯、徐文波、叶丹、毛星星、冯磊

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653100 昆明医科大学第六附属医院医学检验科

653100 昆明医科大学第六附属医院消化内科

糖化血红蛋白 民族 性别 年龄

云南省教育厅科研项目云南省科技厅-昆明医科大学应用基础研究联合专项

2019J1309202001AY070001-096

2024

医学研究杂志
中国医学科学院

医学研究杂志

CSTPCD
影响因子:0.702
ISSN:1673-548X
年,卷(期):2024.53(3)
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