石榴补血糖浆治疗缺铁性贫血的临床疗效观察
Clinical Efficacy Observation of Pomegranate Blood Replenishing Syrup in the Treatment of Iron Deficiency Dnemia
田文灏 1郎海燕 1王金环 2孙长岗 3侯丽 1李冬云 1陈信义 1马薇1
作者信息
- 1. 100700 北京中医药大学第一临床医学院
- 2. 150040 哈尔滨,黑龙江中医药大学附属第一医院
- 3. 261041 潍坊市中医院
- 折叠
摘要
目的 探讨石榴补血糖浆治疗缺铁性贫血的临床疗效和安全性.方法 采用多中心、随机、开放、阳性药物对照方法,将2020年6月1日～2023年3月1日收治的气血两虚型缺铁性贫血120例患者随机分为治疗组(n=90)和对照组(n=30).治疗组给予石榴补血糖浆,对照组给予生血宝合剂.比较两组的临床疗效、中医证候及不良事件.结果 治疗组的临床疗效有效率为52.22％,优于对照组的30％,差异有统计学意义(P＜0.05);治疗8周后,治疗组血红蛋白水平提升高于对照组,差异有统计学意义(P＜0.05);中医证候疗效方面,治疗组总有效率为82.22％,优于对照组的40.00％,差异有统计学意义(P＜0.05).两组患者均没有发生不良事件.结论 石榴补血糖浆治疗气血两虚型缺铁性贫血患者的临床疗效显著,且具有良好的临床安全性.
Abstract
Objective To investigate the clinical efficacy and safety of pomegranate blood replenishing syrup in the treatment of iron deficiency anemia.Methods Using a multicenter,randomized,open,positive drug-controlled method,120 patients with iron deficien-cy anemia of the qi and blood deficiency type admitted from June 1,2020 to March 1,2023 were divided into the treatment group(n=90)and the control group(n=30),with pomegranate blood replenishing syrup was given to the patients in treatment group and shengshu-bao combination was given to the patients in control group.The clinical efficacy,Chinese medicine evidence and adverse reactions were compared between the two groups.Results The effective rate of the treatment group was 52.22％,which was better than 30％of the con-trol group,and the difference was statistically significant(P＜0.05).The hemoglobin level of the treatment group was higher than that of the control group after 8 weeks of treatment,and the difference was statistically significant(P＜0.05);in terms of TCM syndrome effica-cy,the total effective rate of the treatment group was 82.22％,which was better than 40.00％of the control group,and the difference was statistically significant(P＜0.05).There were no adverse events in either group.Conclusion For patients with iron deficiency anemia of the qi and blood deficiency type,pomegranate blood replenishing syrup has obvious clinical efficacy and good clinical safety.
关键词
石榴补血糖浆/缺铁性贫血/气血两虚/临床疗效Key words
Pomegranate blood replenishing syrup/Iron deficiency anemia/Q i and blood deficiency/Clinical efficacy引用本文复制引用
基金项目
国家中医药管理局高水平中医药重点学科建设项目(zyyzdxk-2023268)
出版年
2024
NETL
NSTL
万方数据