Objective The upper airway structure of the human is complicated.The deformation&displacement and interaction of the internal structures are not only reflected in the sagittal plane,but the change in other direction also affects the airway collapse and obstruction of the patient with obstructive sleep apnea hypopnea syndrome(OSAHS).Therefore,a three-dimensional model of the patient's upper airway established is expected to accurately describe the natural sleep state and conforms to the physiological compliance,which is the basis for the biomechanical simulation analysis of the fluid-structure coupling in the upper airway,and has practical application value for clinical diagnosis and evaluation.Methods In this paper,CT data of the OSAHS patient's upper airway in supine position during natural sleep were used to complete three-dimensional reconstruction with software,such as Mimics,Geomagic and HyperMesh etc.Results Three-dimensional finite element model of the upper airway(including nasopharynx airway and oral airway)and surrounding soft tissues(including soft palate,tongue and epiglottis)was established.The three-dimensional upper airway model is consistent with the real geometrical morphology and the physiological compliance of the patient with OSAHS during natural sleep.Conclusion The nasopharyngeal airway and oral airway were both established,which is conducive to the subsequent analysis of the impact of different respiratory patterns on OSAHS,and provides numerical model support for further exploring the mechanical mechanism of the airway obstruction during sleep in OSAHS patients.
关键词
阻塞性睡眠呼吸暂停低通气综合征/自然睡眠期/生理顺应性/三维重建/数字医学
Key words
Obstructive sleep apnea hypopnea syndrome/Nature sleep/Physiological compliance/Three-dimensional reconstruction/Digital medicine
维普
万方数据