摘要
目的:探讨宫颈弹性成像技术在自发性早产孕妇孕期检查中的应用价值.方法:选取 2021 年 8 月—2023 年 8 月在徐州市中心医院超声科进行常规产检的 431 例孕妇为研究对象,所有孕妇均随访至分娩,且在孕期内定期进行超声检查.利用宫颈弹性成像技术对所有孕妇进行产前超声检查并记录宫颈在孕期内的变化.根据孕妇孕周及分娩时间,将孕妇分为足月产组和早产组,回顾性比较两组孕妇宫颈参数的变化.结果:两组孕妇在入组时的一般资料差异无统计学意义,在孕 20~24 周,早产组孕妇的宫颈长度低于足月产组(3.67±0.55 vs 4.21±0.61),差异有统计学意义,且这种现象在孕晚期持续存在(3.34±0.71 vs 3.94±0.52).早产组孕妇的宫颈硬度比(76.54±6.21)在孕 20~24 周也低于足月产组(83.34±5.14),差异有统计学意义(P<0.05).早产组孕妇的对比指数和宫颈内口应变平均值在孕 20~24 周和孕 28~35 周也与足月产组比较差异有统计学意义(P<0.05).结论:宫颈弹性成像技术可以在孕中晚期对孕妇宫颈状况进行筛查,提示可能出现的自发性早产的发生,在临床中具有一定的研究价值.
Abstract
Objective To explore the application value of cervical elastography in the prenatal examination of pregnant women with spontaneous preterm birth.Methods A total of 431 pregnant women who underwent routine prenatal examinations in the ultrasound department of Xuzhou Central Hospital from August 2021 to August 2023 were selected as the research subjects.All pregnant women were followed up until delivery and underwent regular ultrasound examinations during pregnancy.Cervical elastography was used to conduct prenatal ultrasound examinations on pregnant women and record the changes in the cervix during pregnancy.Based on the gestational weeks and delivery time,pregnant women were divided into full-term delivery group and preterm birth group,and the changes in cervical parameters between the two groups were compared.Results There was no statistically significant difference in the general characteristics of the two groups of pregnant women at enrollment.However,during the gestational weeks of 20-24,the cervical length of pregnant women in the preterm birth group was lower than that in the full-term delivery group(3.67±0.55 vs 4.21±0.61),and this difference was statistically significant.This phenomenon persisted in the late stages of pregnancy(3.34±0.71 vs 3.94±0.52).The cervical stiffness index of pregnant women in the preterm birth group(76.54±6.21)was significantly lower than that in the full-term delivery group(83.34±5.14)during gestational weeks 20-24.There were also significant differences in the contrast index and average strain of the cervical internal os between the preterm birth group and the full-term delivery group during gestational weeks 20-24 and 28-35(P<0.05).Conclusion Cervical elastography can be used in the mid-to-late stages of pregnancy to screen for cervical conditions in pregnant women and has certain research value in predicting the occurrence of spontaneous preterm birth in clinical practice.
基金项目
徐州市卫生健康委科技项目(E-cervixTM)(XWKYHT20210559)