Objective To explore the application value of echocardiography in evaluating the therapeutic effect of transcatheter aortic valve replacement in patients with aortic valve disease.Methods A total of 144 patients with aortic valve disease who were to be treated with transcatheter aortic valve replacement in Liaocheng Second People's Hospital from June 2021 to June 2023 were selected.According to the types of preoperative aortic valve lesions,the patients were divided into incomplete closure group and stenosis group,and were evaluated by echocardiography before and after surgery,to analyze the value of echocardiography in evaluating the effect of transcatheter aortic valve replacement in patients with aortic valvular disease.Results The results showed that the left ventricular end systolic volume,left ventricular end diastolic volume,aortic valve regurgitation,effective aortic valve regurgitation port,aortic valve regurgitation area,and aortic valve regurgitation diameter in the group with incomplete closure were all lower than before surgery,and the differences were statistically significant(P<0.05).The effective aortic valve orifice area increased in the stenosis group one month after surgery,and the maximum cross valve pressure difference and maximum velocity above the aortic valve were lower than that before surgery,with statistically significant differences(P<0.05).Conclusion Echocardiography has certain application value in evaluating the therapeutic effect of transcatheter aortic valve replacement in patients with aortic valve disease.