Objective To investigate the diagnostic efficacy and related parameters of diffusion-weighted magnetic resonance imaging in benign and malignant solid pulmonary nodules.Methods A total of 55 patients(58 lung lesions)with pulmonary nodules detected by MRI were collected from Yangxin County Hospital of Traditional Chinese Medicine from September 2021 to September 2023.Puncture biopsy was performed on 58 lung lesions and used as the gold standard to analyze the diagnostic efficacy and related parameters of MRI diffusion weighted imaging(DWI)in benign and malignant solid pulmonary nodules.Results Among 58 lung lesions in 55 patients,43 malignant lesions and 15 benign lesions were detected by puncture biopsy.The sensitivity,specificity and accuracy of MRI in the diagnosis of benign and malignant solid pulmonary nodules were 92.50%,93.33%and 92.73%,with Kappa value =0.824,high consistency with gold standards.The apparent diffusion coefficient(ADC)of patients with malignant solid pulmonary nodules was lower than that of benign solid pulmonary nodules,and the lesion to spinal cord DWI signal intensity ratio(LSR)was higher than that of benign solid pulmonary nodules,with statistical significance(P<0.05).The AUC values of ADC,LSR and their combination in the diagnosis of benign and malignant solid pulmonary nodules were 0.708,0.731 and 0.814,respectively,all of which had certain diagnostic value.Conclusion Magnetic resonance diffusion-weighted imaging has a higher diagnostic efficacy in benign and malignant pulmonary solid nodules,with ADC value and LSR value being its related parameters.