Objective To explore the diagnostic value of diffusion weighted magnetic resonance imaging(DWI-MRI)in acute cerebral infarction.Methods Retrospective analysis of clinical data of 80 suspected acute cerebral infarction patients admitted to Jinan Third People's Hospital from February to December 2023 was performed.All patients underwent cranial magnetic resonance imaging(MRI)and DWI-MRI examination.Used clinical comprehensive diagnostic results as the gold standard,the diagnostic efficacy of conventional MRI and DWI-MRI in acute cerebral was compared to calculate the consistency with the gold standard,to compare the detection rates of conventional MRI and DWI-MRI for cerebral infarction at different stages,to compare the apparent diffusion coefficient(ADC)values of the affected and healthy sides of patients with cerebral infarction at different stages.Results The diagnostic value of DWI-MRI technology for acute cerebral infarction was higher than that of conventional MRI examination,and the difference was statistically significant(P<0.05).The consistency between routine MRI examination and gold standard diagnosis was poor(Kappa value=0.232).The diagnostic consistency between DWI-MRI examination and gold standard was good(Kappa value=0.857).There was no statistically significant difference(P>0.05)in the detection rates of hyperacute and acute phase cerebral infarction among different examination methods.The ADC value on the affected side in the hyperacute phase was lower than that in the acute phase,while the ADC value on the healthy side was higher than that in the acute phase,with a statistically significant difference(P<0.05).Conclusion DWI-MRI has high clinical application value in the diagnosis of acute cerebral infarction,and can further clarify the patient's condition through the analysis of ADC,providing effective reference for clinical diagnosis and treatment.