摘要
目的:探讨弥散加权成像(DWI)结合合成磁共振成像(syMRI)对乳腺良恶性肿瘤的鉴别诊断价值.方法:选取2020年5月—2022年3月桂林医学院附属医院收治的69例乳腺肿瘤患者.所有患者术前均行MRI检查,包括平扫、DWI和syMRI MAGiC序列(组织T1、T2 和PD值快速定量).绘制受试者工作特征(ROC)曲线,分析表观弥散系数(ADC)值和syMRI值及两参数联合对乳腺良恶性疾病的诊断效率.结果:69例乳腺肿瘤患者中恶性53例(76.8%),良性16例(23.2%).良恶性肿瘤ADC值与T1、T2 值比较,差异有统计学意义(P＜0.05).经ROC曲线分析独立参数ADC、T1、T2 和联合参数的曲线下面积分别为 0.903、0.703、0.818、0.956.联合参数(ADC值和T1、T2 值)的诊断效率高于单参数ADC值(P＜0.05).结论:DWI联合syMRI可提高乳腺良恶性肿瘤的鉴别效率.
Abstract
Objective To investigate the value of diffusion weighted imaging(DWI)combined with synthetic magnetic resonance imaging(syMRI)in the differential diagnosis of benign and malignant breast tumors.Methods 69 breast cancer patients admitted to Guilin Medical College Affiliated Hospital from May 2020 to March 2022 were selected.All patients underwent preoperative MRI,including plain scan,DWI,and syMRI MAGiC sequences(rapid quantification of tissue T1,T2,and PD values).receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic efficiency of apparent diffusion coefficient(ADC)and syMRI values and the combination of the two parameters in benign and malignant breast diseases.Results Among 69 patients with breast tumors,53(76.8%)were malignant and 16(23.2%)were benign.ADC values and T1 and T2 values between benign and malignant tumors(P<0.05).The area under the curve for the ROC analysis of the independent parameters ADC,T1,T2,and the combined parameters were 0.903,0.703,0.818,and 0.956,respectively.The diagnostic efficiency of the combined parameters(ADC values and T1 and T2 values)was higher than the single-parameter ADC values(P<0.05).Conclusion DWI combined with syMRI can improve the differential efficiency of benign and malignant breast tumors.
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