Objective Assess the characteristics of Hashimoto thyroiditis combined with thyroid cancer using ultrasound,and analyze the ultrasound characteristics of thyroid cancer nodules in different states of thyroid function.Methods A retrospective analysis of 80 patients(86 nodules)diagnosed with Hashimoto thyroiditis combined with thyroid nodules who visited the Hebei General Hospital from August 2016 to November 2018.All nodules were judged for benign or malignant nature through fine-needle aspiration or surgical pathology.Based on the pathological results,the ultrasound characteristics of thyroid cancer were analyzed.The ultrasound characteristics of Hashimoto thyroiditis combined with thyroid cancer were compared among groups with normal thyroid function,hypothyroidism,and hyperthyroidism.Results In the context of Hashimoto thyroiditis,there were 44 cases of patients with benign thyroid nodules(benign group)and 42 cases of thyroid cancer patients(malignant group).There were statistically significant differences in echogenicity,shape,margin,axial ratio,and calcification between the benign and malignant groups(P<0.05).When compared the hypothyroid group with the normal and hyperthyroid groups,there were statistically significant differences in the calcification of thyroid cancer nodules in the context of Hashimoto thyroiditis(P<0.05),with a higher rate of malignancy associated with focal calcification signs in the hypothyroid group.Conclusion Hypoechoic,irregular shape,ill-defined margins,axial ratio≥1,and focal calcification are important characteristics in the ultrasound diagnosis of malignant thyroid nodules associated with Hashimoto thyroiditis.A high index of suspicion for malignancy is warranted when hypothyroidism is combined with focal calcifications.
Hashimoto thyroiditisThyroid cancerUltrasonic diagnosisThyroid function
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