Objective To investigate the imaging characteristics of eosinophilic hepatic infiltration (EHI) utilizing enhanced CT,Gd-diethylenetriamine pentametric acid (Gd-DTPA) enhanced MRI,and gadolinium ethoxybenzyl diethyle netriamine pentaacetic acid (Gd-EOB-DTPA) enhanced MRI. Methods Patients with EHI in Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine between May 2015 and April 2024 were selected for a retrospective analysis. The clinical data and imaging information of the patients were collected. Evaluations were made regarding to the numbers of lesion,distribution,size,shape,margin,density or signal characteristic,enhancement parttern and other special features. Spearman correlation analysis was used to analyze the relationship between peripheral blood eosinophil counts and hepatic lesion numbers. Results A total of 14 EHI patients were identified,a total of 115 lesions were documented,with 2 cases of solitary lesions and 12 cases of multiple lesions. There was a positive correlation between lesion count and eosinophil levels (r=0.547,P<0.05). The maximum diameter of the lesions ranged from 3 to 73 mm,with indistinct margins and predominantly wedge-shaped morphology,mainly located subcapsularly. Enhanced CT/MRI scans showed progressive,centripetal enhancement,with notable features such as vascular penetrating sign,striping sign and ring sign. Gd-EOB-DTPA showed partial uptake in hepatobiliary phase,with lesion boundaries appearing smaller and shape altered compared to T2WI-FS images. Conclusion Imaging findings of EHI patients displayed distinctive characteristics,including progressive and centripetal enhancement,vascular penetrating sign,striping sign,and ring sign. The partial uptake of gadoxetic acid disodium in hepatobiliary phase,along with reduced lesion size and shape changes compared to T2WI-FS images,are major features. This partial uptake is significant for differentiating EHI from neoplastic lesions.
维普
万方数据
