Optimization of dynamic countercurrent extraction of the continuous production process for processed Epimedium based on orthogonal experiment
Objective:In order to make full use of the therapeutic effect of Bromidi and practice the new theory of continuous production of traditional Chinese medicine,the continuous production process of dynamic countercurrent extraction was studied..Methods:Based on L8(2)7 orthogonal test,the dynamic countercurrent extraction and continuous production process of Bromidi Epimedium was optimized.Results:The optimal dynamic countercurrent extraction continuous production process was as follows:Coarse particle size 1-5 mm,infiltration time 30min,feeding spiral advance speed 5 r/min,extraction solvent adding flow 75 L/h,extraction spiral advance speed 1-3 r/min,extraction time 90min,extraction temperature 100℃,The extraction yield was 19.37%,the transfer rate of paucariin I was 46.14%,the total transfer rate was 63.24%,and the extract was 23.07%.Conclusion:The optimal dynamic countercurrent extraction of Bromidi has good reproducibility,high content transfer rate and simple operation.It provides a reference for the application of a new production model for continuous production of Chinese medicine with dynamic countercurrent extraction.
grilled epimediumdynamic countercurrent extractioncontinuous production modetransfer rate of paucariin i contentextractum