It is essential to understand the product and process correctly in the design of a drug workshop.The conditions needed for a particular process significantly affect the equipment layout and,therefore,the overall facility layout.This article describes the development history of insulin products briefly,and generally introduces the process and facility design of current mainstream products.In view of the complex purification process and large dosage of class A reagent used,an actual project was used to explain and elaborate the design methods of an insulin API workshop.
Recombinant Human Insulinexpression systemfermentationProcessPurificationDesign