Research on the Improvement of Povidone Iodine Complexation Process Based on Solid Phase Heating Method
Study the Povidone iodine complexation process to improve the effective iodine content of the product.Optimize the best complexation process conditions through the quality screening of polyvinylpyrrolidone and the design of orthogonal tests,the process was improved to obtain the optimal reaction conditions:the water content of PVP is 3.5％-4.1％,and the particle size D90 is 49 μm;the ratio of iodine to PVP in the complexation process is 1∶7,the reaction temperature is 18 hours,and the reaction temperature is 75 ℃.The results show that the effective iodine content of the improved product is 9.1％-12.1％higher than that of the existing product,and the process is stable and feasible,which is suitable for large-scale commercial production.
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维普
