医用生物力学2024,Vol.39Issue(4) :712-717.DOI:10.16156/j.1004-7220.2024.04.021

基于体外实验的光电容积脉搏波信号检测及脉率特性

Photoplethysmography Pulse Wave Signal Detection and Pulse Rate Characteristics Based on an in vitro Experiment

何卫俊 刘雍陶 刘登吉 尹凯 贺缨 迟青卓 母立众
医用生物力学2024,Vol.39Issue(4) :712-717.DOI:10.16156/j.1004-7220.2024.04.021

基于体外实验的光电容积脉搏波信号检测及脉率特性

Photoplethysmography Pulse Wave Signal Detection and Pulse Rate Characteristics Based on an in vitro Experiment

何卫俊 1刘雍陶 1刘登吉 1尹凯 1贺缨 1迟青卓 1母立众1
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作者信息

  • 1. 大连理工大学 能源与动力学院,海洋能源利用与节能教育部重点实验室,辽宁 大连 116024
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摘要

目的 借助体外循环实验系统的可控参数优势考察血流参数变化对脉率特性的影响.方法 建立一套搭载腕部体外模型的人体循环系统,通过分别改变心率、腕部流量、压力和系统顺应性等参数,从腕部模型中获取光电容积脉搏波信号,并提取脉率变异性的时域和频域指标.结果 心率、压力和系统顺应性的改变会引起脉搏波形状的改变,但能够表明脉率变异性的时域指标NN50、PNN50 数值为 0,其他指标以及频域指标都处在极低值范畴.结论 在未有心率变异性时,心率、腕部流量、血压和系统顺应性等血流动力学变化未产生明显的脉率变异性.本研究可为临床在更便利的腕部采集设备加持下开展更多脉率变异性和心率变异性研究提供参考.

Abstract

Objective To investigate the influence of changes in blood flow parameters on pulse rate characteristics by taking the advantage of controllable parameters in an experimental cardiopulmonary bypass system.Methods A set of human circulatory system equipped with an in vitro wrist model was established.By changing parameters such as the heart rate,wrist flow,pressure,and system compliance,a photoplethysmography pulse wave signal was obtained from the wrist model,and the time-and frequency-domain indices of pulse rate variability were extracted.Results Changes in heart rate,pressure,and system compliance caused a change in pulse shape,but the time domain indices NN50 and PNN50,which indicate pulse rate variability,were zero,and the other indices and frequency domain indices were in the very low value category.Conclusions In the absence of heart rate variability,hemodynamic changes in heart rate,wrist flow,blood pressure,and system compliance did not produce significant pulse rate variability.This study can provide a reference for studies on pulse rate variability and heart rate using more convenient wrist acquisition equipment.

关键词

脉率变异性/光电容积脉搏波/循环系统体外模型/血流动力学

Key words

pulse rate variability/photoplethysmography pulse wave/circulatory system model in vitro/hemodynamics

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基金项目

中央高校基本科研业务费专项(DUT22YG206)

国家自然科学基金(51976026)

出版年

2024
医用生物力学
上海第二医科大学

医用生物力学

CSTPCD北大核心
影响因子:0.858
ISSN:1004-7220
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